Showing posts with label Biochemistry. Show all posts
Showing posts with label Biochemistry. Show all posts
Harper's Illustrated Biochemistry
Harper's Illustrated Biochemistry (LANGE Basic Science), 26 Edition
McGraw-Hill Medical | ISBN 0071389016 | March 2003 | 693 Pages | 7,93 Mb
A good and very well known book about biochemistry
Extensively revised and updated, this authoritative biochemistry text is known worldwide for its comprehensive and up-to-date coverage. Extensively illustrated and user-friendly, the text offers examples pf how knowledge of biochemistry is essential for understanding the molecular basis of health and disease. The 26th edition also features expanded content on results of the Human Genome Project. Perfect as both text and USMLE review.
Harper's Illustrated Biochemistry
Harper's Illustrated Biochemistry
McGraw-Hill Medical | ISBN 0071389016 | March 2003 | 693 Pages | PDF 6,7 Mb
Extensively revised and updated, this authoritative biochemistry text is known worldwide for its comprehensive and up-to-date coverage. Extensively illustrated and user-friendly, the text offers examples pf how knowledge of biochemistry is essential for understanding the molecular basis of health and disease. The 26th edition also features expanded content on results of the Human Genome Project. Perfect as both text and USMLE review.
Biochemistry: The Molecular Basis of Life
Trudy McKee, James R. McKee, "Biochemistry: The Molecular Basis of Life" (3rd edition)
McGraw-Hill | ISBN 007231592X | 2002 Year | DjVu | 21,28 Mb | 800 Pages
McGraw-Hill | ISBN 007231592X | 2002 Year | DjVu | 21,28 Mb | 800 Pages
| “ | This textbook is intended for a diverse audience that ranges from chemistry majors to students in any of the life sciences. The logical organization (discussion of molecular structure immediately followed by the role it plays in metabolism) leads students through the complex world of biochemistry while an impressive art program helps to guide them through up-to-date concepts. Of special interest are the new Biochemical Methods boxes in the text, PowerPoint slides for instructors, and animated and annotated Chime structures of biomolecules in the OLC. | ” |
Biochemistry
Reginald H. Garrett, Charles M. Grisham, "Biochemistry" (2nd edition)
Harcourt Brace, Custom Publishers | ISBN 0030758173 | 1999 Year | PDF | 24,6 Mb | 851 Pages
Harcourt Brace, Custom Publishers | ISBN 0030758173 | 1999 Year | PDF | 24,6 Mb | 851 Pages
| “ | In Biochemistry, the questions can be more revealing than the answers. This Second Edition offers a unique conceptual and organizing framework, "Essential Questions." Guiding students through the density of the material by the use of section head questions, supporting concept statements, and summaries, this focused approach is supported by unparalleled text/media integration through BiochemistryNow, providing students with a seamless learning system. Beautifully and consistently illustrated, the Third Edition gives science majors the most current presentation of biochemistry available. Written by a chemist and a biologist, the book presents biochemistry from balanced perspectives. | ” |
Lehninger Principles of Biochemistry
David L. Nelson, Michael M. Cox, "Lehninger Principles of Biochemistry" (4th Edition)
W. H. Freeman | ISBN 0716743396 | 2004 Year | DjVu | 37 Mb | 1100 Pages
W. H. Freeman | ISBN 0716743396 | 2004 Year | DjVu | 37 Mb | 1100 Pages
| “ | There basically are two top contenders for the #1 position for a biochemistry textbook: Lehninger vs Voet. At first sight, the 1650+ pages Voet text for 'chemistry' oriented students seems like it is too much for the competition. So, how can Lehninger do better in 1100 pages? There are several factors at play, and the 4th edition of Lehninger simply dominates Voet and the rest of the biochem texts out there as follows. The Lehnninger text has a long history, but given that biochemical knowledge doubles every 5 years or so, it matters what a text offers now, not in the past. The writing style is simple, direct, engaging, not too easy but neither too esoteric. The principles (as the title suggests) and the unity in diversity are emphasized, so that the student understands biochemical principles not merely facts, acronyms, pathways. The graphics are very professional. They are comparable to any review article in hot journals such as Nature, Science, Cell, etc. The rendering of protein surfaces, and the different angles through which a structure is seen is outstanding (a good example is the section on the ribosome). The structures have been rendered from the PDB (protein data bank) coordinates. Most are rendered in the ribbon representation, but in many cases the surface is rendered in grey, depending on the level of detail. Contrast this with the 3rd edition of Voet: the authors have not bothered to re-render their graphics, most are identical to the 1995 edition, a time when people only cared if you could generate a structure. Voet's graphics are not done uniformly; the backgrounds can be white, grey, black, some structures are taken directly from the original literature and vary widely in the format and rendering. It is not enough that Voet updated the text on biochemical developments from 1995-2004. The Lehninger pages on the most important protein folds, for example, are very helpful in giving the student a feel for the fold, the domain composition, the size, and names of model proteins one is expected to encounter over and again in the research literature. But pretty pictures are not the only thing that sets Lehninger apart from the rest. The material is distilled such that almost the same ammount of information is contained in this text, even though Voet is 50% bigger. There can be no such text as "Advanced Biochemistry" for grad students etc. -- if one is looking for that sort of thing, then one should purchase a life sciences encyclopedia. For undergraduates, any text is bound to be a bit overwhelming, but Lehninger is clear enough that the above average student should assimilate the material preparing for an exam without too much confusion or difficulty. I also like the typesetting in Lehninger much better than Voet, which again, uses the same boring format as the 2nd 1995 edition. The quality of paper is good in both texts. Lehninger's text feels like the space is utilized well, whereas Voet's space is a bit overcrowded, though strangely, some of the Voet structures are too large, and take up too much space. Lehninger encompases all the new developments up to 2004: RNAi, genomes, new facts on controversial enzyme mechanisms etc. Speaking of enzyme mechanism, both texts do a good job in deriving the Michaelis-Menten equation step by step rather than simply saying something like "through trivial algebra eqn 34 transforms into 45". The literature reference section of Lehninger is one of the best parts of the text: the references are a mixture of classic, outstanding work, and recent review materials, which should guide the more curious student to navigate the overwhelming ammount of information in modern biochemistry and molecular biology. I loved the numerous photos of key players in biochemistry. For example, Francis Crick is shown as a young man when the text refers to the model for DNA, and as a middle aged man in another chapter. The historical emphasis is well placed. The "working in biochemistry" boxes are similarly relevant and well placed. I only wish the current authors had added a brief sketch of Albert Lehninger. In fact, they do not mention the history of the text, which is a little strange. The text contains brief solutions to all the end-of-chapter problems so the solutions manual (unfortunately titled "The Absolute, Ultimate Guide...") is not really neccessary for the good student. I think the criticism that Voet is 'tougher' and has more 'chemistry' in it is not entirely fair. Any researcher cannot expect to find his/her answers for a particular mechanism in any textbook -- that's the whole point of research. The principles on the other hand, can be sufficiently explained with a selection of enzymes and their mechanism, which Lehninger delivers. The metabolism middle part of the book is a bit too large, but it is difficult to avoid this, as when it boils down to it, molecular biophysics and biology have to account for the behavior of a particular system. Grad students these days tend to ignore metabolism, but as they mature, they start to see its point (and the memory slowly starts to assimilate all these enzymes, substrates, products, inhibitors, conditions, pathways...). Voet, of course, also covers metabolism in a comprehensive way. In conclusion, contrary to what Voet reviewers said to "supplement Lehninger with Voet", I am suggesting students get a copy of Lehninger, either from the library or by purchasing their own copy, to supplement any biochemistry text with Lehninger. There is no other text out there that comes close to Lehninger. Which leads to the natural question, "why are there 10-20 biochem books currently in print?". Well, I certainly hope Lehninger will drive out of print most of them. | ” |
Biochemistry, 5th Edition
ISBN: 0716746840 |Title: Biochemistry, 5th Edition, 2002-02| Author: Jeremy M. Berg, John L. Tymoczko, Lubert Stryer |Publisher: W. H. Freeman| pages: 1100| PDF 26.18 MB
Reviewer:
This is a superb book to understand the excitement in biochemistry and to understand its relevance to human health. Stryer's book presents biochemistry in a completely different manner. Instead of traditionally presenting one topic after the other, it presents each chapter giving a representative molecule or system for explanation and characterization of the material in that chapter . For example, heamoglobin and myoglobin for explaining the three dimensional structure of proteins, lysozyme and chymotrypsin for explaining enzyme action, and a host of others. Each example is critically chosen, considering its role and function in life and metabolism. This makes the matter very interesting and practical. Paralleling this are given descriptions of diseases and biochemical disorders as well as historical perspectives. The last part, molecular physiology, gives a lucid exposition of the fundamental biochemical processes in living organisms. In fact, the whole point of view in the book is a physiological one. The book is unlike Lehninger, which is essentially a traditional textbook. Even though Lehninger is great as an introductory book, Stryer is, in my opinion, the book to read if you want to learn biochemistry as a discipline which should be viewed as an exciting excursion into human metabolism and life.
Review of new edition (Berg, Tymockzo):
I had written a favourable review earlier for a previous edition of Stryer. I rest my case for the latest edition too. Jeremy Berg and John Tymoczko, both accomplished authors, join Lubert Stryer in producing this time tested and comprehensive book. If you are someone like me, who believes that enzymes and proteins are the key to understanding the mysteries of life, then this book is for you. While it may not have as much coverage of nucleic acid chemistry biochemistry as some of the other books, I believe that the next revolution in biology is going to hinge upon our understanding of SYSTEMS. And while an understanding of genes is crucial as enabling knowledge, if you really consider all the actual action that happens in biochemical systems, almost all of it is mediated by enzymes and receptors. Stryer's new edition has literally hundreds of pictures and discussions of proteins and enzymes which explain the structure and function of these magnificent biological agents. The book has still retained the concise and yet comprehensive style which made its previous edition so good. Again, the book strikes a good balance between textbook and medical biochemistry, which is its great strength. Small boxes and side discussions throw light on the most interesting events connected with drug metabolism and disease. As a side point, the discussions about nucleic acid biology which the authors HAVE included are pretty good in themselves. Biochemistry is one of the most exciting branches of scientific research. This is because first of all it is highly interdisciplinary, enjoying a wonderful synergy with organic and inorganic chemistry, physical chemistry and physics, and of course, biology. Secondly, Biochemistry is an extraordinarily dynamic subject and biochemical knowledge doubles every five years. Discoveries in biochemistry directly affect medical science. In the 21st century, it continues to promise us radical understanding into the working of life, and any good biochemistry book should ideally convey this excitement to the reader. This one does. The bottom line is, if you want to get excited about the miracle that is called life, and want to do it in a rational way, Stryer is still one of the very best. I hope it continues to be so.
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